Preliminary Program

Thursday 6th of July

08h45 - 09h00 Welcome - N Winter/ D Brand (codirectors FéRI)

9h-9h30 Keynote Muriel Vayssier-Taussat (Initiative PREZODE) – « One Health : where are we ? »

Session 1: Interaction du bioagresseur avec les cellules de l'hôte
Chairman/woman : Ignacio Caballero-Posadas (INRAE Tours) and Catherine Gaudy-Graffin (University of Tours)

9h30-10h00 Nolwenn Jouvenet (Institut Pasteur, Paris) – « Virus and Interferons : clash of the titans ».

*10h00-10h20 Florent Kempf (SPVB – INRAE Tours) – “Identification of bacterial taxa responsible for negative outcomes will give clues for designing an appropriate microbiota capable of mitigating the infection outcome. (BAMI)”.

10h20-10h50 Coffee break

10h50-11h10 Mathilde Couteaudier (MAVIVH – University of Tours) – “Role of Hypoxia Inducible Factors (HIFs) on HCV infection in a differentiated cell culture model under physiological hypoxia”.

11h10-11h40 Franck Gallardo (NeoVirTech) – « Development of ANCHORTM Autofluorescent Viruses for Real-Time Visualization of Infection and Viral Replication in Live Cells ».

Session 4: Therapy and resistance

*11h40-12h00 Maxime Vallée (INSERM U1070 – University of Poitiers) – “Tissue distribution of Ceftazidime-Avibactam in kidney tissue in heathy rats and pigs using a microdialysis technique”.

12h00 - 13h00 Lunch

13h00 - 13h30 Poster Session 1

13h30-13h50 Yohann Lacotte (RESINFIT – University of Limoges) – “PROMISE, a One Health meta-network to fight antimicrobial resistance in France”.

13h50 – 14h10 Magali Garcia (LITEC - University of Poitiers) and Philippe Chouteau (MAVIVH - University of Tours) – FéRI’s prize 2021 – « Role of hypoxia in skin model infection with Usutu virus ».

Session 2: Mécanismes de virulence et adaptation hôte-pathogène
Chairwoman/man : Foteini Koutroumpa (INRAE Tours) and Thibault Josse (University of Tours)

14H10-14h40 Emilie Brasset (GRED, University of Clermont-Ferrand) - “Reactivation of an errantivirus in Drosophila ovarian somatic tissue: from germline invasion to taming”.

14h40-15h00 Anne Silvestre (AIM - INRAE Tours) – “Overexpression of Eimeria tenella ROP kinase 2 induces an early production of schizont”.

15h00-15h30 Coffee break

15h30-15h50 Corentin Mallet (BioVA - INRAE Tours) – “Imaging hypoxia in avian skin and response of chicken keratinocytes to hypoxia in vitro”.

15h50-16h10 Claude Charvet and Rodrigo Guabiraba (MPN & 3iMO - INRAE Tours) – “Deciphering the role of 5-aminovalerate, a neuroactive metabolite produced by the chicken microbiota”.

*16h10-16h30 Julie Tottey (AIM - INRAE Tours) – “Functional characterisation of cysteine cathepsins as new virulence factors in the apicomplexan parasite Cryptosporidium parvum”.

16h30-17h00 Christian Pellevoisin (MATTEK) - “Physiological 3D models of the respiratory and intestinal systems for studying host-pathogen interactions”

Friday 7th of July

8h30-9h00 Keynote lecture - Jimmy Bordarie (University of Tours – Quality of life and psychological health) - "Vaccination intention: feedback on hidden variables of a complex equation".

Session 3: Réactions inflammatoires et immunitaires de l’hôte
Chairwoman/man :  Isabelle Couillin (University of Orléans) and Christophe Paget (University of Tours)

9h00-9h30 Pr. William Horsnell (Cape Town University) – « Maternal transfer of immunity against infection to offspring ».

09h30-9h50 Nicolas Riteau (INEM – University of Orléans) – “Chronic ozone exposure induces lung inflammation through NLRP6-dependent activation of pyroptotic and necroptotic pathways”.

9h50-10h10 Sandra Khau (CEPR – University of Tours) – “Inflammasome regulation during bacterial and fungal superinfection in cystic fibrosis”.

10h10-10h40 Coffee break

10h40-11h00 Emilie Doz-Deblauwe (IBIR – INRAE Tours) – "IFNg pathway is essential for the immunosuppressive activity of regulatory neutrophils".

11h00-11h20 Françoise Bussière (AIM - INRAE Tours) – “The caecal microbiota promotes the acute inflammatory response and the loss of the intestinal barrier integrity during severe Eimeria tenella infection”.

11h20-11h40 Dorian de Moura Rodrigues (INEM – University of Orléans) – “Protective role of STING in Idiopathic Pulmonary Fibrosis (IPF)”.

11h40-12h10 Marc Dubourdeau (Ambiotis, SAS) - "Specialized pro resolving mediators at the crossroads between inflammation and immunity"

12h10 - 13h10 Lunch

13h10 – 13h40 Poster Session 2

13h40-14h00 Guillaume De Nerville (AFFILOGIC) - "You can run, but you can’t hide! Hitting targets with Nanofitins".

Session 4: Thérapies et résistance
Chairwomen : Malika Mekhalfi (University of Orléans) and Sandra Da Ré (University of Limoges)

14h00-14h30 Cyril B. Dousson (Ai-biopharma) - “An antiviral drug discovery case study: barrier to resistance and learnings”. 

*14h30-14h50 Maxime Vallée (INSERM U1070 – University of Poitiers) – “Tissue distribution of Ceftazidime-Avibactam in kidney tissue in heathy rats and pigs using a microdialysis technique”.

14h50-15h10 Adélaïde Chesnay (CEPR – University of Tours) – « Impact de la combinaison Elexacaftor-Tezacaftor-Ivacaftor sur les atteintes aspergillaires au cours de la mucoviscidose ».

15h10-15h30 Coffee break

15h30-15h50 Brice Le Gallou (BRMF – INRAE/University of Tours) – “Nanopore sequencing of full-length 16S rDNA for bacterial diagnosis of brain abscesses”.

15h50-16h10 Adeline Cezard (CEPR – University of Tours) – “Identification of a host metabolite with both antiviral and anti-inflammatory properties that protects against influenza virus-driven morbidity and mortality”.

16h10-16h40 Graciela Andrei (Rega Institut) - “Drug-resistance highlights the need for novel antivirals against DNA viruses”.

16h40 General scientific days conclusion with the FéRI prizes awarding for the best oral communication and poster

 *collaborative projects competing for the 2023 FéRI Prize